Peer-Reviewed Publications

 

  1. Shin, M.; Shukla, S.; Chung, Y.H.; Beiss, V.; Chan, S.K.; Ortega-Rivera, O.; Wirth, D.M.; Chen, A.; Sack, M.; Pokorski, J.K.; Steinmetz, N.F. “The Roadmap of COVID-19 Vaccine Development and a Potential Nanomaterial Path Forward”, 2020, In Press at Nature Nanotechnology

  2. Church, D.C.; Takiguchi, L.; Pokorski, J.K.* "Optimization of Ring-Opening Metathesis Polymerization (ROMP) under Physiologically Relevant Conditions", Polymer Chemistry, 202011, 4492-4499.

  3. Van de Voorde, K.M.; Pokorski, J.K.*; Korley, L.T.J.* “Exploring morphological effects on the mechanics of blended PLA/PCL extruded fibers fabricated using multilayer coextrusion”, Macromolecules, 202013, 5047-5055.

  4. Church, D.C.; Pokorski, J.K.* “Cell Engineering with Functional Poly(oxanorbornene) Block Copolymers”, Angewandte Chemie, 202059, 11379-11383.

  5. Wirth, D.M.; Jaquez, A.; Gandarilla, S.; Hochberg, J.D.; Church, D.C.; Pokorski, J.K.* “A Highly Expandable Foam for Lithographic 3D Printing”, ACS Applied Materials and Interfaces, 2020, 12, 19033-19043.

  6. Lopez, M.A.; Soto, R.F.; Wang, C.; Rueda, R.; Shukla, S.; Silva‐Lopez, C.;  Kupor, D.;  McBride, D.A.;  Pokorski, J.K.;  Nourhani, A.; Steinmetz, N.F.;  Shah, N.J.;  Wang, J. "Built-in Active Microneedle Patch with Enhanced Autonomous Drug Delivery", Advanced Materials2020, 1905740.

  7. Wirth, D.M.; Pokorski, J.K.* “Design and Fabrication of a Low-Cost Pilot-Scale Melt-Processing System”, Polymer2019, 121802

  8. Pokorski, J.K.; Hore, M.J. “Structural Characterization of Protein-Polymer Conjugates for Biomedical Applications with Small-Angle Scattering”, Current Opinion in Colloid and Interface Science, 2019, 42, 157-168.

  9. Zheng, Y.; Lee, P.W.; Wang, C.; Thomas, L.D.; Stewart, P.L.; Steinmetz, N.F.*; Pokorski, J.K.* “Freeze Drying to Produce Efficacious CPMV Virus-like Particles”, Nano Letters, 2019, 19, 2099-2105.

  10. Pokorski, J.K.*, Smith, L.E. “ ‘Click’ Chemistry for Medicine and Biology”, Molecular Pharmaceutics, 2018, 15, 2891. (Editorial for special issue in honor of M.G. Finn’s 60th birthday)

  11. Purwar, M.; Pokorski, J.K.; Singh, P; Bhattacharyya, S; Arendt, H; DeStefano, J; La Branche, C.C.; Montefiori, D.C.; Finn, M.G.; Varadarajan, R. “Design, display and immunogenicity of HIV1 gp120 fragment immunogens on Qβ virus like particles”, Vaccine201836, 6345-6353. 

  12. Hutnick, M.A.; Pokorski, J.K.* “Polymeric Interventions for Microbial Infections: A Review”, Molecular Pharmaceutics, 2018, 15, 2910–2921.

  13. Zheng, Y.; Lucius-Dougherty, M.; Konkolewicz, D.; Steinmetz, N.F.; Pokorski, J.K.* “Green Nanofillers: Plant Virus Reinforcement in Hydrophilic Polymer Composites”, Polymer2018142, 72-79.

  14. Lee, P.W.; Pokorski, J.K.* “PLGA Devices: Production and Applications for Sustained Protein Delivery”, WIRES Nanomedicine and Nanobiotechnology, 2018; e1516, DOI:10.1002/wnan.1516 (Invited Review)

  15. Wallat, J.D.; Harrison, J.K.; Pokorski, J.K. “pH Responsive Doxorubicin Delivery by Fluorous Polymers for Cancer Treatment”, Molecular Pharmaceutics, 201815, 2954–2962.

  16. Czapar, A.E; Tiu, B.D.; Veliz, F.A.; Pokorski, J.K.; Steinmetz, N.F. “Slow-release formulation of cowpea mosaic virus for in situ vaccine delivery to treat ovarian cancer”, Advanced Science2018, DOI:10.1002/advs.201700991

  17. Lee, P.W.; Maia, J.; Pokorski, J.K.* “Milling Solid Proteins to Enhance Activity After Melt-Encapsulation”, International Journal of Pharmaceutics2017533, 254-265.

  18. Lee, P.W.; Shukla, S.; Wallat, J.D.; Danda, K.C.; Maia, J.; Steinmetz, N.F.; Pokorski, J.K.* “Virus-like Particle Laden Biodegradable Implants Prepared via Melt Processing”, ACS Nano,  201711, 8777-8789.

  19. Jordan, A.M.; Kim, S.E.; Van de Voorde, K.; Pokorski, J.K.; Korley, L.T.J. "In Situ Fabrication of Fiber Reinforced Three-Dimensional Hydrogel Tissue Engineering Scaffolds", ACS Biomaterials Science and Engineering20173, 1869-1879.

  20. Kim, S.E.; Lee, P.W.; Pokorski, J.K.* “Biologically Triggered Delivery of EGF from Polymer Fiber Patches” ACS Macro Lett.20176, 593-597.

  21. Johansen, M.; Gao, Y.; Hutnick, M.A.; Craig, S.E.L.; Pokorski, J.K.; Flask, C.A.; Brady-Kalnay, S.M. “Quantitative Molecular Imaging with a Single Gd-based Contrast Agent Reveals Specific Tumor Binding and Retention In Vivo”, Anal. Chem.201789, 5932-5939.

  22. Wallat, J.D.; Wek, K.; Chariou, P.; Carpenter, B.L.; Ghiladi, R.A.’ Steinmetz, N.F.; Pokorski, J.K.* “Fluorinated Polymer-Photosensitizer Conjugates Enable Improved Generation of ROS for Anticancer Photodynamic Therapy”, Polymer Chemistry20178, 3195-3202.

  23. Kim, S.E.; Jordan, A.M.; Korley, L.T.J.; Pokorski, J.K.* “Drawing in poly(ε-caprolactone) fibers: tuning mechanics, fiber dimensions and surface-modification density”, J. Mat. Chem. B.20175, 4499-4506. *Highlighted in the emerging investigators themed collection

  24. Cyphert, E.; Wallat, J.D.; Pokorski, J.K.; von Recum, H.V. “Erythromycin modification thatimproves its acidic stability while optimizing it for local drug delivery”, Antibiotics2017, Apr 25;6(2). pii: E11. doi: 10.3390/antibiotics6020011

  25. Lee, P.W.; Isarov, S.A.; Wallat, J.D.; Molugu, S.K.; Shukla, S.; Sun, J.E.P.; Zhang, J.; Zheng, Y.; Lucius Dougherty, M.; Konkolewicz, D.; Stewart, P.L.; Steinmetz, N.F.; Hore, M.J.A.; Pokorski, J.K.* “Polymer Structure and Conformation Alter Immune Recognition of Virus-like Particle-Polymer Conjugates”, J. Am. Chem. Soc.2017139, 3312-3315. * Featured as cover art and as a JACS Spotlight

  26. Hutnick, M.A.; Ahsanuddin, S.; Guan, L.; Lam, M.; Baron, E.; Pokorski, J.K.* “PEGylated Dendrimers as Drug Delivery Vehicles for Photosensitizer Silicon Phthalocyanine Pc 4 for Candidal Infections”, Biomacromolecules2017, 18, 379–385.

  27. Wallat, J.D.; Czapar, A.E.; Wang, C.; Wen, A.M.; Wek, K.S.; Yu, X.; Steinmetz, N.F.; Pokorski, J.K.* “Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles”, Biomacromolecules201718, 103-112. 

  28. Tiu, B.D.; Kernan, D.L.; Tiu, S.B.; Wen, A.M.; Zheng, Y.; Pokorski, J.K.; Advincula, R.C.; Steinmetz, N.F. “Electrostatic layer-by-layer construction of fibrous TMV biofilms for applications in medicine”, Nanoscale20179, 1580-1590.

  29. Chen, Q.; Mangadlao, J.D.; Wallat, J.D.; De Leon, A.; Pokorski, J.K.; Advincula, R.C. “3D Printing Biocompatible Polyurethane/Poly(lactic acid)/Graphene Oxide Nanocomposites: Anisotropic Properties”, ACS Applied Materials and Interfaces2017, 9, 4015–4023.

  30. Rahman, M.A.; Lee, P.W.; Zhang, C.; Pokorski, J.K.; Baer, E. “Polyolefin Microfiber Based Antibacterial Fibrous Membrane by Forced Assembly Coextrusion”, Macromolecular Materials and Engineering2017302, DOI: 10.1002/mame.201600304

  31. Jordan, A.M.; Viswanath, V.; Kim, S.E.; Pokorski, J.K.; Korley, L.T.J.“Processing and surface modification of polymer nanofibers for biological scaffolds: a review”, J. Mat. Chem. B2016, 4, 5958-5974.

  32. Isarov, S.A.; Lee, P.W.; Towslee, J.H.; Hoffman, K.M.; Davis, R.D.; Maia, J.M.; Pokorski, J.K.* “DNA as a Flame Retardant Additive for Low-Density Polyethylene”, Polymer201697, 504-514.

  33. Chariou, P.L.;  Lee, K.L.; Pokorski, J.K.; Saidel, G.M.; Steinmetz, N.F. “Diffusion and Uptake of Tobacco Mosaic Virus as Therapeutic Carrier in Tumor Tissue: Effect of Nanoparticle Aspect Ratio”, J. Phys Chem B2016120, 6120-6129.

  34. Kim, S.E.; Zhang, C.; Advincula, A.A.; Baer, E.; Pokorski, J.K.* “Protein and Bacterial Antifouling of Melt Coextruded Nanofiber Mats”, ACS Applied Materials and Interfaces20168, 8928-8938.

  35. Isarov, S.A.; Lee, P.W.; Pokorski, J.K.* “‘Graft-to’ Protein:Polymer Conjugates Using Polynorbornene Block Copolymers”, Biomacromolecules201617, 641-648.

  36. Isarov, S.A.; Pokorski, J.K.* “Protein ROMP: Aqueous Graft-from Ring-Opening Metathesis Polymerization”, ACS Macro Letters20154, 969-973. *Highlighted as cover art

  37. Herrmann, K.; Johansen, M.; Craig, S.; Vincent, J.; Howell, M.; Gao, Y.; Lu, L.; Erokwu, B.; Agnes, R. Lu, Z-R.; Pokorski, J. K.; Basilion, J.; Gulani, V.; Griswold, M.; Flask, C.; Brady-Kalnay, S. “Molecular imaging of tumors using a quantitative T1 mapping technique”, Diagnostics20155(3), 318-332.

  38. Lee, P.W.; Towslee, J.H.; Maia, J.; Pokorski, J.K.* “PEGylation to Improve Protein Stability During Melt Processing”, Macromolecular Bioscience2015, 15, 1332-1337.

  39. Kim, S.E.; Wallat, J.D.; Harker, E.C.; Advincula, A.A.; Pokorski, J.K.* “Multifunctional and Spatially Controlled Bioconjugation to Melt Coextruded Nanofibers”, Polymer Chemistry20156, 5683-5692. (Highlighted in the Emerging Investigators Special Themed Issue)

  40. Lee, K.L.; Shukla, S.; Wu, M.; Ayat, N.R.; El Sanadi, C.E.; Wen, A.M.; Edelbrock, J.F.; Pokorski, J.K.; Commandeur, U.; Dubyak, G.R.; Steinmetz, N.F. “Stealth Filaments: polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X”, Acta Biomaterialia201519, 166-179.

  41. Kim, S.E.; Harker, E.C.; De Leon, A.C.; Advincula, R.C.; Pokorski, J.K.* “Coextruded, aligned, and gradient-modified poly(ℇ-caprolactone) fibers as platforms for neural growth”, Biomacromolecules201516, 860-867.

  42. Kim, S.E.; Wang, J.; Jordan; A.M.; Korley, L.T.J.; Baer, E.; Pokorski, J.K.* “Surface Modification of Melt Extruded Poly(ℇ-caprolactone) Nanofibers: Toward A New Scalable Biomaterial Scaffold”, ACS Macro Letters20143, 585-589.

  43. Wallat, J.D.; Rose, K.A.; Pokorski, J.K.* “Proteins and Substrates for Controlled Radical Polymerization”, Polymer Chemistry2014, 5, 1545-1558. *Highlighted as cover art

  44. von Recum, H.A.; Pokorski, J.K.* “Peptide and Protein based inhibitors of HIV Co-receptors”, Experimental Biology and Medicine2013, 238, 442-449.

  45. Pokorski, J.K.; Appella, D.H. “Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA”, Journal of Nucleic Acids2012, vol. 2012, Article ID 971581 (Invited Article). 

  46. Wen, A.M.; Ryan, M.J.; Yang, A.C.; Breitenkamp, K.; Pokorski, J.K.; Steinmetz, N.F. “Photodynamic activity of viral nanoparticles conjugated with C60”, Chem Commun2012, 48, 9044-9046.

  47. Nicolaou, K.C.; Valiulin, R.A.; Pokorski, J.K.; Chang V.; Chen, J.S.; “Bio-inspired synthesis and biological evaluation of a colchicine-related compound library” Bioorg. Med. Chem. Lett.201222, 3776-3780.

  48. Pokorski, J. K.; Hovlid, M. L.; Finn, M.G. “Cell Targeting with Hybrid Qβ Virus-Like Particles Displaying Epidermal Growth Factor”, ChemBioChem2011, 12, 2441-2447.

  49. Pokorski, J. K.; Breitenkamp, K.; Liepold, L. O.; Qazi, S.; Finn, M.G. “Functional Virus-BasedPolymer-Protein Nanoparticles by Atom Transfer Radical Polymerization”, J. Am. Chem. Soc. 2011, 133, 9242-9245.

  50. Pokorski, J. K.; Steinmetz, N. F. “The Art of Engineering Viral Nanoparticles” Mol. Pharm. 2011, 8, 29-43.

  51. Pokorski, J. K.; Miller Jenkins, L. M.; Feng, H.; Durell, S.R.; Bai, Y.; Appella, D.H. “Introduction of a triazole amino acid into a peptoid induces turn formation in aqueous solution”, Org. Lett. 20079, 2381-2383.

  52. Witschi, M. A.; Pokorski, J. K.; Appella, D. H. “Peptide nucleic acid (PNA) microarrays made with (S,S)-trans-cyclopentane-constrained peptide nucleic acids”, Methods Enzymol2006410, 189-200.

  53. Guler, M. O.; Pokorski, J. K.; Appella, D. H.; Stupp, S. I. “Enhanced oligonucleotide binding to self-assembled nanofibers”, Bioconjugate Chem200516, 501-503.

  54. Pokorski, J.K.; Nam, J.M.; Vega, R. A.; Mirkin, C.A.; Appella, D.H. “Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection”, Chem. Commun200516, 2101-2103.

  55. Pokorski, J.K.; Myers, M.C.; Appella, D.H. “Cyclopropane PNA: observable triple melting in a PNA constrained with a three-membered ring”, Tet. Lett200546, 915-917.

  56. Myers, M.C.; Pokorski, J.K.; Appella, D.H. “Polyamine nucleic acids: Peptide nucleic acids with a flexible secondary amine in the backbone maintain oligonucleotide binding affinity”, Org. Lett2004, 6, 4699-4702.

  57. Pokorski, J.K.; Witschi, M.A.; Purnell. B.L.; Appella, D.H. “(S,S)-trans-cyclopentane-constrained peptide nucleic acids. A general backbone modification that improves binding affinity and sequence specificity”, J. Am. Chem. Soc2004126, 15067-15073.

Book Chapter

  1. Glidden, M.D., Edelbrock, J.F., Wen, A.M., Shukla, S., Ma, Y., French, R.H., Pokorski, J.K., Steinmetz, N.F., Application of engineered viral nanoparticles in materials and medicine, in Chemoselective and Bioorthogonal Ligation Reactions: Concepts and Applications, Wiley-VCH, 631-710. DOI: 10.1002/9783527683451.ch18

Jon Pokorski    |    858.246.3183    |    jpokorski@ucsd.edu